Catalog Products » IGF2BP2 Antibody, mAb, Rabbit
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IGF2BP2 Antibody, mAb, Rabbit

RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation.Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability.
$210.00
A04788-50

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Overview
Specificity This product is specific to IGF2BP2
Host Species Rabbit
Immunogen A synthesized peptide derived from human IGF2BP2
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated
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Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunohistochemistry Frozen (IHF) 1:50-1:200
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Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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IGF2BP2 Antibody, MAb, Rabbit

Western blot analysis of IMP2 expression in (1) SH-SY5Y cell lysate; (2) Mouse heart lysate. »

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Background
Target Background RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation.Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability.
Synonyms gf2bp2; IMP2; p62; VICKZ2;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.