CCL19 Antibody, mAb, Rabbit
| $210.00 | |
| A04814-50 | |
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| Ask us a question | |
IVD Raw Materials
| $210.00 | |
| A04814-50 | |
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| Ask us a question | |
| Specificity | This product is specific to CCL19 |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human CCL19 |
| Species Reactivity | Human |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
Western blot analysis of CCL19 expression in Human Macrophage Inflammatory Protein 3 beta recombinant protein lysate. »
| Target Background | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Synonyms | CCL19; CK beta 11; CKb11; ELC; Exodus3; MIP3 beta; MIP3B; SCYA19; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.