Catalog Products » p-STK4/3 (T183/T180) Antibody, mAb, Rabbit
Manual
Manual
COAs

p-STK4/3 (T183/T180) Antibody, mAb, Rabbit

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
$210.00
A05094-50

Ask us a question
Overview
Specificity This product is specific to p-STK4/3 (T183/T180)
Host Species Rabbit
Immunogen A synthesized peptide derived from human STK4 around the phosphorylation site of T183
Species Reactivity Human
Conjugate Unconjugated
Back

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Back

Properties
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
Back

P-STK4/3 (T183/T180) Antibody, MAb, Rabbit

Western blot analysis of Phospho-MST1/MST2 (T183 + T180) expression in (1) HeLa cell lysate treated with Calyculin A; (2) HepG2 cell lysate treated with Calyculin A. »

<
>

Background
Target Background Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Synonyms KRS1; KRS2; MST1; MST2; STK3; STK4; YSK3;
Back

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.