Catalog Products » GMP Anti-Human CD28 Antibody (F105), mAb, Mouse
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GMP Anti-Human CD28 Antibody (F105), mAb, Mouse

*This product has been discontinued!*
This product is specific for Human CD28
GMPA02213
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Specificity This product is specific for Human CD28
Host Species Mouse
Immunogen Recombinant Human CD28
Conjugate Unconjugated
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ex vivo cell culture process; Flow cytometry
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Form Liquid
Storage Buffer Supplied in 10 mM Sodium Citrate, 150 mM NaCl, pH 6.5.
Concentration 5 mg/ml
Storage Instructions The product remains stable at -70 ± 10 °C. Avoid repeated freeze-thaw cycles. Please refer to the COA for specific expiry date.
Isotype Mouse IgG1κ
Clonality Monoclonal
Clone ID F105
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Appearance Clear, colorless liquid
pH 6.5 ± 0.5
Concentration 5.0 ± 0.5 mg/ml tested by A280 nm
Purity ≥ 95.0% as analyzed by SEC-HPLC
Sequence The coverage of the light chain and heavy chain sequence was 100% consistent with the theoretical amino acid sequence by mass spectrometry (MS)
Residual HCP ≤ 100.0 ng/mg by ELISA method
Residual HCD ≤ 10.0 pg/mg by quantitative PCR method
Residual Protein A ≤ 10.0 ng/mg by ELISA method
Endotoxin Level < 0.1 EU/mg by gel clotting method
Sterility No growth
Reactivity Qualified
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Target Background CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. It plays an important role in cell proliferation and cytokine production and promotion of T-cell survival. It also enhances the production of IL-4 and IL-10 in T cells in conjunction with TCR/CD3 ligation and CD40L co-stimulation.
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For laboratory research and ex vivo cell isolation and culture applications. Direct human use, including taking orally and injection and clinical use are forbidden.