Protein Services for Early Drug Discovery

Active, purified proteins that can sustain functional analysis and assay development are critical to the discovery of drug targets and therapeutic proteins. However, many of these active proteins, particularly emerging and newly discovered candidates, are not commercially available and thus have to be custom made. GenScript offers a complete industrial solution for all protein expression and purification issues. GenScript's multiple protein expression systems, including bacterial, yeast, baculoviral, and mammalian systems, are available on both small and large scales. Proteins that require glycosylation may be best suited to our insect and mammalian expression systems. Our large scale capabilities can provide pharmaceutical customers with high-purity active proteins of any quantity for target discovery, target validation, high-throughput screening (HTS), and structure-function studies. Our streamlined processes apply multiple approaches to expression optimization and allow us to offer highly competitive prices on custom protein projects.

Advantages of GenScript:

• As one of the pioneers of the biology services industry, GenScript has the most experience and the best understanding of its pharmaceutical customers' needs.
• GenScript's one-stop service eliminates the customers' need to search for qualified suppliers of different services and removes redundant procurement and legal work.
• GenScript offers a secure, easy, and state-of-the-art online ordering and project tracking system.

Key Features and Services:

• Diverse expression systems:

Bacteria

Yeast

Baculovirus/insect cells

Mammalian cells

• Large-scale protein production services:

Fermentors

Wave mixers

Bioreactors

• High-expression, stable cell lines in yeast, insect and mammals
• Recombinant baculovirus generation
• Membrane preparation
• Large-volume transient transfection
• Large-volume frozen transients for high-throughput screening (HTS)
• ¹⁵N- and ¹³C- labeled protein expression
• Multiple protein purification options:
  • Affinity column (GST, Ni-IDA, protein A, G, or L resins)
  • Gel filtration
  • Ion exchange
  • Hydrophobic column
  • HPLC

Quotations and Ordering:

To request a quotation, please download and complete the Quotation/Order Form, and send it to us by email or fax.

To order, please download and complete the Quotation/Order Form and send it to us by email or fax with a formal PO (Purchase Order) or credit card information. You can also submit PO/credit card information by phone or via our secure online messaging system.

If submitting samples, please mail them together with a hard copy of the completed Quotation/Order Form to: Protein Services, GenScript, 120 Centennial Ave., Piscataway, NJ 08854, US.

For questions, or to inquire about the status of your order contact us by email, phone, fax or via our secure online messaging system.

Our customer service representatives are available 24 hours a day, Monday through Friday to assist you.

	Email: protein@genscript.com
	Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
	Fax: 1-732-210-0262 1-732-885-5878