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endotoxin removal

Endotoxin Removal System

Endotoxin (LPS) is released primarily upon cell lysis when bacterial cell dies can make up the majority of pyrogens. Endotoxin removal is especially important when performing immunological readouts and developing manufacturing processes because endotoxin can cause false readings in cell based assays and there are limits to the amount of endotoxin allowed in human products. It is always desirable to rapidly and effectively remove pyrogen from pharmaceutical products, recombinant proteins produced in E. coli (or other gram negative bacteria), and tissue culture media.

GenScript's proprietary kits is designed based on separation matrix of modified polymyxin B (PMB). The sample can be purified from the contaminating endotoxins. Such simple and efficient steps in the process involves column activation and equilibration, etc. (please refer to the work-flow on the right), and the final endotoxin level can be reduced to below 0.1 EU/ml with repeated use of ToxinEraser™ endototoxin removal tool.

Key Features

  • High binding capacity at least 2, 000, 000 EU / ml (CV)
  • High Recovery Yield: >90% with minimized sample loss
  • High stability and high removal efficiency

endotoxin removal

Ordering Information

Cat. No.
Product Name
Size
Price
Quantity
L00338 ToxinEraserTM Endotoxin Removal Kit
1 kit
$110.00

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Cat. No.
Product Name
Size
Price
Quantity
L00402 ToxinEraserTM Endotoxin Removal Resin
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M01063 ToxinSensorTM Endotoxin-free Pipette Tips (1 ml, Blue)
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M01053 ToxinEraserTM Regeneration Buffer
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