Kinase Assay Services
Kinases play many important roles in cellular signaling pathways and various other complex processes involving phosphorylation. The dysregulation of kinases is often associated with pathogenic pathways of many diseases, such as cancer, inflammatory diseases, neural disorders, and many metabolic disorders. Protein kinases have extraordinary potential as drug targets.
GenScript provides a series of kinase assay services aiming to accelerate your drug discovery processes involving kinase targets. |
Featured Services:
- Assay Development
- Assay Reagent Preparation
- Compound Screening
|
GenScript also provides Ki determination, substrate determination, and research collaboration services.
|
Assay Setup Showcases:
|
|
|
Name: EGFR T790M
Source: Human
Substrate: Abl1 peptide substrate (EAIYAAPFAKKK)
Reference Compound: H-89
Method: HTRF
Testing: 8 conc. at n = 2
|
|
Name: PKA
Source: Human
Substrate: Kemptide peptide substrate (LRRASLG)
Reference Compound: H-89
Method: HTRF
Testing: 8 conc. at n = 2
|
|
Kinase Assay Catalog:
GenScript is developing kinase catalog assays for all the listed kinases. The number of ready kinase catalog assays is increasing. For catalog assay detail, please click the links.
If you can’t find kinase of interest in ready catalog assays, please feel free to contact us for support.
* Available as catalog kinase products for order. See kinase products.
|
|
Serine/Threonine Kinases
AGC
CaMK
CMGC
Family |
Name |
| CDK |
CDK1/Cyclin B1 |
| CDK1/Cyclin E |
| CDK2/Cyclin A |
| CDK2/Cyclin E |
| CDK3/Cyclin E |
| CDK4/Cyclin D1 |
| CDK4/Cyclin D3 |
| DyrK |
HIPK2 |
| GSK |
GSK3α |
| GSK3β * |
| JNK |
JNK1 |
| JNK2 |
| JNK3 |
| MAPK |
ERK1 |
| ERK2 |
| p38α |
| p38β |
TKL
Family |
Name |
| B-RAF |
B-RAF |
| B-RAF V600E |
| RAF1 |
RAF1 Y340D/Y341D |
| IRAK |
IRAK4 |
| TGFβ |
ACVR1 |
|
STE
Family |
Name |
| MAP4K/STE20 |
PAK1 |
| PAK2 |
| PAK3 |
| MINK1 |
| MST1 |
| MEK |
MEK1/MAPKK1 |
Others
Family |
Name |
| Aurora |
Aurora-A |
| CaMKK |
CaMKK1 * |
| IKK |
IKKα |
| IKKβ |
| IKKε |
| NEK |
NEK7 |
| PLK |
PLK1 |
| PLK3 |
Tyrosine Kinases
RTK
Family |
Name |
| AXL |
TYRO3/SKY |
| Eph Kinase |
EPHA1 |
| EPHA2 |
| EPHA3 |
| EPHA4 |
| EPHA5 |
| EPHA7 |
| EPHB1 |
| EPHB2 |
| EPHB3 |
| EPHB4 |
| EGFR |
EGFR |
| EGFR T790M |
| HER2/ERBB2 |
| HER4/ERBB4 |
| FGFR |
FGFR1 |
| FGFR2 |
| FGFR3 |
| FGFR4 |
| TIE |
TIE2/TEK |
| SEV |
ROS1 * |
| InsR |
INSR |
| IGF-1R |
| IRR |
| MET |
MET |
| PDGFR |
KIT |
| CSF1-R |
| PDGFRα |
| PDGFRβ |
| FLT3 |
| FLT3 ITD |
| RET |
RET |
| SEV |
ROS1 |
| TIE |
TIE2/TEK |
| TRK |
TRK-A |
| TRK-B |
| TRK-C |
| VEGFR |
VEGFR1 |
| VEGFR2 |
| VEGFR3 |
| MUSK |
MUSK |
| DDR |
DDR2 |
CTK
Family |
Assay |
| ABL |
ABL1 |
| ABL1 T315L |
| ACK |
ACK1 * |
| CSK |
CSK |
| SRC |
BLK |
| FYN |
| LYN |
| LCK |
| SRC * |
| SYK |
ZAP-70 |
|
| Cat. No. |
Service |
Price (USD) |
SC1395 |
Custom Kinase Assay Services |
|
Quotations and Ordering:
 For quotations, you may contact us by email (bioassay@genscript.com), phone (1-732-885-9188 or Toll-Free: 1-877-436-7274), fax (1-732-210-0262), or via our Secure Online Messaging System.
Orders can be placed by email, phone or fax either a PO (Purchase Order) or credit card.
Our customer service representatives are available 24 hours a day, Monday through Friday to assist you.
 |
Email: bioassay@genscript.com |
 |
Phone: 1-877-436-7274 (Toll-Free), 1-732-885-9188 |
 |
Fax: 1-732-210-0262, 1-732-885-5878 |
|
