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*For Non-Clinical Research Use Only*
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Substance P (1-4)  |
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| Full Name |
Substance P (1-4) |
Sequence
(one-letter code) |
RPKP |
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Sequence
(three-letter code) |
{ARG}{PRO}{LYS}{PRO} |
| Description |
Substance P is an 11-amino acid polypeptide with the sequence{Arg}{Pro}{Lys}{Pro}{Gln}{Gln}{Phe}{Phe}{Gly}{Leu}{Met}-NH2. In the central nervous system, Substance P has been associated with the regulation of mood disorders, anxiety, stress, reinforcement, neurogenesis, respiratory rhythm, neurotoxicity, nausea/emesis,and pain.Subtance P also works as a potent vasodilator. These effects are caused by the release of nitric oxide from the endothelium. This release can cause hypotension. Substance P is involved in the transmission of pain impulses from peripheral receptors to the central nervous system. It has been theorized that it plays a part in fibromyalgia. Capsaicin has been shown to reduce the levels of Substance P, probably by reducing the number of C-fiber nerves or rendering these nerves more tolerant. |
| Purity |
> 95% |
| Storage |
Store Substance P at -20°C. Keep container tightly closed. |
| Notes |
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Related Products
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1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
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2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
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3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
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4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
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Document-MSDS: 4882_20080710230830.PDF (PDF)