|
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Hot Products
*For Non-Clinical Research Use Only*
|
[Pro 9]-Substance P  |
|
|
| Full Name |
[Pro9]-Substance P |
| Alias |
[Pro9]-SP |
|
Sequence
(one-letter code) |
RPKPQQFFPLM-NH2 |
Sequence
(three-letter code) |
{ARG}{PRO}{LYS}{PRO}{GLN}{GLN}{PHE}{PHE}{PRO}{LEU}{MET}-NH2 |
| C-Terminal |
NH2 |
| Description |
[Pro9]-substance P ([Pro9]-SP) possesses has very good affinity for NK-1 binding sites and that, in contrast to substance P, it interacts selectively with these sites. [Pro9]-SP had neither agonist nor antagonist properties on NK-2 and NK-3 receptors. Indeed, it did not stimulate phosphoinositide turnover on the hamster urinary bladder (NK-2 assay) and was devoid of activity on the contraction of the rabbit pulmonary artery (NK-2 assay) and of the rat portal vein (NK-3 assay). As a result of its high selectivity, [Pro9]-SP thus appears an excellent tool for investigating the functional properties of NK-1 receptors. |
| Purity |
> 95% |
| Storage |
Store at -20°C. Keep tightly closed.
|
| Notes |
|
Related Products
 |
1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
|
2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
|
3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
|
4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
|
|
Document-HPLC: 1970_20060721145614.PDF (PDF)
