Sarafotoxin 6c

*This product has been discontinued!*

S6c, as a selective ETB endothelin receptor agonist. its administration can cause a transient fall in mean arterial blood pressure (MABP) prior to occlusion and attenuated the fall in MABP induced by coronary occlusion.

Cat. No.	RP12761
Size	Buy in bulk

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Overview Properties

Synonyms

SRTX-c

Note

Most acidic. Causes strong vasoconstriction of the coronary vessels as well as various changes in the ECG that lead to A-V block and cardiac arrest.

Overview

Cas No	121695-87-2
Sequence	{CYS}{THR}{CYS}{ASN}{ASP}{MET}{THR}{ASP}{GLU}{GLU}{CYS}{LEU} {ASN}{PHE}{CYS}{HIS}{GLN}{ASP}{VAL}{ILE}{TRP}
Sequence Shortening	CTCNDMTDEECLNFCHQDVIW (Disulfide bridge: 1-15 and 3-11)
Molecular Formula	C₁₀₃H₁₄₇N₂₇O₃₇S₅
Disulfide Bridge	1-15 and 3-11
Molecular Weight	2515.8

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Properties

Purity	> 95%
Format Bridge	1-15,3-11
Solubility	Insoluble in water. Peptide is very acidic.Rehydrate 100 mg of peptide with at least 1ml of pH8.0 buffer orrehydrate the content with 30 ml-100 ml DMSO - then dilute up the content with water to the desired concentration.
Storage	Store at -20°C. Keep tightly closed. Store in a cool dry place.

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