β-Amyloid A4 Protein Precursor (740-770), APP (C31)

*This product has been discontinued!*

This peptide, C31, consists of 31 amino acids and corresponds to the C-terminal fragment of the amyloid precursor protein (APP). The generation of this C31 peptide through the cleavage of APP by caspase is associated with neuronal death linked to Alzheimer’s disease. In addition, this peptide is a potent inducer of apoptosis and is located in lipid rafts together with APP-BP1, a binding protein for APP’s intracellular domain.

Cat. No.	RP20165
Size	Buy in bulk

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Overview Properties

Synonyms

Beta-Amyloid A4 Protein Precursor (740-770), APP (C31)Aβ(740-770), APP (C31)

Overview

Sequence	{Ala}{Ala}{Val}{Thr}{Pro}{Glu}{Glu}{Arg}{His}{Leu}{Ser}{Lys} {Met}{Gln}{Gln}{Asn}{Gly}{Tyr}{Glu}{Asn}{Pro}{Thr}{Tyr}{Lys} {Phe}{Phe}{Glu}{Gln}{Met}{Gln}{Asn}
Sequence Shortening	AAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Molecular Formula	C₁₆₂H₂₄₃N₄₅O₅₂S₂
Molecular Weight	3717.1

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Properties

Storage

Store at -20°C. Keep tightly closed. Store in a cool dry place.

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