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Cat. No.
Name
Size   
Price
Selected
RP20211-1
HCV NS3 Protease Substrates 1
1 mg
$644
RP20211-5
HCV NS3 Protease Substrates 1
5 mg
$2898
HCV NS3 Protease Substrates 1

Full Name HCV NS3 Protease Substrates 1
Alias
HCV NS3 Protease Substrates 1
Documents
Document-MSDS: 8934_20081209042518.PDF (PDF)
Document-HPLC: 10539_20090824070136.PDF (PDF)
Document-MS: 10540_20090824070144.PDF (PDF)
Figures
Reference
Sequence
(one-letter code)
EAGDDIVPCSMSYTWTGA
Sequence
(three-letter code)
{Glu}{Ala}{Gly}{Asp}{Asp}{Ile}{Val}{Pro}{Cys}{Ser}{Met}{Ser}{Tyr}{Thr}{Trp}{Thr}{Gly}{Ala}
Description
This peptide mimicking the NS5A-5B cleavage junction of the nonstructural protein (NS) is an efficient substrate used by Shimuzu et al. to detect NS3 protease activity in a standard assay (Km = 411 mM and Kcat = 0.14 min-1, without NS4 activator). Cleavage occurs between Cys and Ser. The cleavage products are analyzed by RP-HPLC.
Purity
> 95%
Storage
Store at -20°C. Keep tightly closed. Store in a cool dry place.
Notes
1
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