Bacterial Sortase Substrate III, Abz/DNP

*This product has been discontinued!*

The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DNP)-NH2, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges.

Cat. No.	RP20431
Size	Buy in bulk

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Overview Properties

Description

The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DNP)-NH₂, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges.

Overview

Sequence	Abz-{Leu}{Pro}{Glu}{Thr}{Gly}{Lys(Dnp)}-NH₂
Sequence Shortening	Abz-LPETG-K(Dnp)-NH₂
Molecular Formula	C₄₁H₅₇N₁₁O₁₄
C Terminal	Amidation
N Terminal	Abz/DNP
Molecular Weight	928.0

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Properties

Purity	> 95%
Storage	Store at -20°C. Keep tightly closed. Store in a cool dry place.

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