Peptide Library Services |  |  | | | Peptide library is a systematic combination of different peptides in large number. It is widely used in drug screening, target validation, epitope mapping, vaccine development, and structure-activity studies. There is an ever increasing demand from large pharmaceutical companies due to the expanding interest in peptide drugs. GenScript peptide library services feature all attributes of proprietary FlexPeptideTM technology, which has materialized into a rapid high-throughput parallel peptide synthesis platform that enables our customers to synthesize larger quantities of high purity peptides at lower cost than traditional methods. GenScript's peptide library services provide flexible selections of peptide purity levels (crude, desalt, >70%, >75%, >80%, >85%, >90%, >95%, and >98%). Each peptide in the library undergoes rigorous quality control to avoid any cross contaminants before delivery. All purified peptides are delivered with complete QC data including RP-HPLC, MS, and COA report to ensure high quality. To meet the growing demand for high throughput peptide library screening, GenScript has recently launched the PepHTSTM Peptide Library Service. PepHTSTM is a proprietary peptide synthesis platform utilizing fmoc chemistry to facilitate enhanced high throughput peptide screening platforms. Large numbers of peptides can be synthesized, and lyophilized in parallel and delivered in a customizable format for an affordable price. All peptide QC is monitored by a stringent Total Quality Management System. In addition, GenScript provides six free online peptide library design tools to help you generate different peptide libraries based on your requirements. GenScript also provides an instant peptide library online quotation system to offer you further efficiency and convenience. | - Services Features
- PepHTSTM Peptide Library
- Design Tools
- Related Services
Key Features: - Competitive prices: Our peptide library services are the most cost-efficient on the market, starting from $29/peptide.
- High-throughput: More than 10,000 peptides per month.
- Flexible purity choices: Crude, desalt, >70%, >75%, >80%, >85%, >90%, >95%, and >98% purity are available to meet your multiple demands.
- No cross-contamination: Peptides are supplied in individual well labeled vials.
- Comprehensive modifications: Our modification service includes labeling, the incorporation of unnatural amino acids, and peptide cyclization with disulfide bridges.
- Stringent quality control: GenScript provides COA, MS and HPLC validation data for each peptide.
- Instant online quotation: Conveniently submit your peptide library requirement through online system.
- One-stop down-stream services: GenScript provides epitope mapping service, binding assay, and functional assay services for your drug discovery research.
Applications: | Antibody epitope mapping and validation | Protein-peptide binding assay | | Peptide biological assay | T-cell epitope discovery | | T-cell epitope mapping and validation | Peptide vaccine development | | Vaccine efficacy testing | Immune monitoring | | Optimization and validation of T-cell assays | Cell therapy approaches | Service Specifications: To meet the different purity demands for multiple applications, we have developed two library service packages: Crude and Purified Peptide Library for your choice. The specifications of the two library services are: Crude Peptide Library (Cat. No.: SC1177) - 1-4 mg ( 5-9 mg, 10-20 mg are also available) for each crude peptide
- Peptide length of 5-20 AA
- Certificate of Analysis, RP-HPLC(optional) and mass spectrum for each peptide
- Modifications including biotin, fluorescence, and unnatural amino acid etc.
- 2-4 weeks typical turnaround time
- Minimum order size is 24 peptides
Purified Peptide Library (Cat. No.: SC1487) - 1-4 mg for each peptide
- Purity: Choice of >70%, >75%, >80%, >85%, >90%, >95%, and >98% by RP-HPLC
- Peptide length of 5-18 AA
- Certificate of Analysis, RP-HPLC and mass spectrum for each peptide
- Modifications including biotin, fluorescence, and unnatural amino acid etc.
- 3-4 weeks typical turnaround time
- Minimum order size is 24 peptides
Delivery Specifications: The typical delivery consists of: - Lyophilized unbound peptides in individual fully labeled vials
- COA, MS and HPLC data
| PepHTSTM Peptide Library For PepHTSTM peptide library service, large numbers of peptides can be synthesized, and lyophilized in parallel and delivered in a customizable format for an affordable price. All peptide QC is monitored by a stringent Total Quality Management System. PepHTSTM is the cost-effective and quality-certified library that you've been searching for. You can download our flyer for PepHTSTM Peptide Library  . PepHTSTM Specifications - Convenient and user-friendly Online peptide library design tools
- High purity: typically >90% or above (other options available)
- No cross-contamination: lyophilized peptides provided in individually clearly-labeled vials
- Comprehensive modifications to enhance peptide diversity and pharmacology: e.g. glycosylation, cyclization, non-natural amino acids, isotope labeling, PEGylation, and more.
- Stringent QC by HPLC and MS for each peptide
PepHTSTM Advantages - High-throughput peptide synthesis and available assay screening
- High success rate comparable with chemical compound libraries
- All peptides produced in modern, state-of-the-art facilities
- Peptide library design consultation services with our experienced chemists
- Comprehensive QA and QC documentation
- Secured data management system
- Dependable quality and fast turnaround
- Customized deliverables and packaging
- Competitive and transparent pricing
Case Study GenScript's PepHTSTM peptide library is a powerful tool for peptide drug screening. GenScript has developed 74 functional cell-based assays for peptide G-protein coupled receptors (GPCRs). All assays are optimized on a FlexStation 3 and/or FLIPR-Tetra platforms and ready for high throughput screening (HTS). Integrating with the PepHTSTM technology, GenScript can offer unique solutions for your peptide drug discovery. Receptor: EDNRA
Source: Human recombinant (CHO cells)
Reference Compound:
Agonist: ET-1 (EC50 =3.9 nM)
Measured Product: Ca2+
Detection Technique: Calcium 4
|  | | GenScript offers six powerful peptide library design tools for epitope mapping and sequence optimization of your peptide research. They are overlapping peptide library, alanine scanning library, truncation library, positional scanning library, random library, and scrambled library.  |
| | Based on advanced peptide library platform which can produce large screening sets of peptides, GenScript also has developed the following down-stream services to offer you one-stop solutions: - Epitope Mapping Service (Cat. No.: SC1500): Using peptide library for epitope discovery and validation to help your antibody drug development and antibody therapeutics research.
- Binding Assay Service: Developing both ordinary and radiometric binding assay services to screen peptide leads that bind target with high affinity in a timely and cost-effective manner.
- Functional Assay Services: Establishing a series of functional assay platforms (GPCR, kinase, ion-channel, and protease) to detect the peptide leads that have biological activity to the drug target.
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Quotations and Ordering:  For quotations, please use our Secure Instant Online Quotation system. You can upload the peptide sequences and choose: - Number of peptides desired
- Minimum quantity and purity requirements
- Modifications and other specifications
 Order can be placed by email, phone, or fax with either a PO (Purchase Order) or credit card. Our customer service representatives are available 24 hours, Monday through Friday to assist you. We accept POs and major credit cards ( ). A 7% New Jersey sales tax will be applied to orders shipped to New Jersey. Your credit card will be billed under "GenScript USA Inc." Click here to download our credit reference form. For international orders, we must apply the full charge at the time the order is placed. In the unlikely event that any given order cannot be filled, our guarantee will take the form of a full refund. | |
