Tumor Cell Line Profiling
Despite decades of active research, cancer remains the most common cause of human deaths especially in developed countries. Hundreds of billions of dollars have been invested in cancer research and development of anti-cancer therapies. Expensive failures of potential blockbuster drugs in clinical trial stage force pharmaceutical companies to pay more attention to preclinical drug development.
More intensive preclinical studies will help you better understand pharmacological mechanism, ease drug safety concerns, evaluate drug efficacy, thereby increasing the success rate in late stages. GenScript offers comprehensive Tumor Cell Line Profiling services as your single solution of anti-cancer drug development. The Tumor Cell Line Profiling services range from high throughput screening (HTS) against pharmacological targets or tumor cell lines to in vitro drug efficacy evaluation.
Tumor Cell Line Profiling Services include:
- Growth Inhibition Assay
- Apoptosis Assay Services
- Cell Line Panel
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Growth inhibition assays are used widely to evaluate the death or life of tumor cells and calculate the potency of anticancer drug candidates. As new inexpensive and high throughput assay methods emerging, cell cytotoxicity/viability assays become more and more popular in primary screening for anticancer drugs.
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Apoptosis, or programmed cell-death, is a normal regulation mechanism in multi-cellular organisms. There are many pathways leading to apoptosis. It's now clear that the pathology of many cancers is linked to the blockings of apoptotic pathways by oncogenic mutations. Finding a compound leading to selective induction of tumor cell apoptosis is very intriguing in anti-cancer drug discovery.
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GenScript collected over 200 human tumor cell lines covering all common cancer types from ATCC and DSMZ. Based on the human tumor cell line panel, GenScript offers comprehensive in vitro tumor cell line profiling and in vivo drug efficacy evaluation services to boost your anticancer drug discovery.
Quotations and Ordering
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