Protease Assay Services
Approximately 500 putative proteases have been identified in human genome. Through controlling complex proteolytic activities, proteases participate in a wide range of physiological processes. Many of them have been utilized as targets for therapeutic intervention, such as Dipeptidyl Peptidase IV (DPP-IV) and HIV-1 protease for diabetes and AIDS, respectively. However, precise roles of many proteases remain unknown in many diseases.
To speed up the drug discovery process that involves protease targets, GenScript has developed a protease assay panel for protease screening and profiling. Moreover, custom assay development service is available to facilitate your drug screening against protease targets of your interest.
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Featured Services:
- Assay Development
- Assay Reagent Preparation
- Compound Screening
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GenScript also provides Ki determination, substrate determination, and research collaboration services. |
Assay Setup Showcases:
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Name: MMP1
Source: Human
Substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2
Reference Compound: NNGH
Method: Spectrofluorimetric
Testing: 10 conc. at n = 2 |
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Name: Factor Xa
Source: Human
Substrate: CH3OCO-D-CHA-Gly-Arg-pNA-AcOH
Reference Compound: PPACK
Method: Spectrophotometric
Testing: 8 conc. at n = 3 |
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Protease Assay Catalog:
GenScript is developing protease catalog assays for all the listed proteases. The number of ready protease catalog assays is increasing. For catalog assay detail, please click the links.
If you can’t find protease of interest in ready catalog assays, please feel free to contact us for support. |
Serine Proteases
Metalloproteases
Protease Family |
Protease Name |
| ACE (Angiotensin Converting Enzymes) |
ACE |
| ACE2 |
| MMPs (Matrix Metalloproteinases) |
MMP1 |
| MMP2 |
| MMP3 |
| MMP7 |
| MMP8 |
| MMP9 |
| MMP10 |
| MMP12 |
| MMP13 |
| MMP14 |
| Other Proteases |
Neprilysin |
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Cysteine Proteases
Protease Family |
Protease Name |
| Caspases |
Caspase-1 |
| Caspase-2 |
| Caspase-3 |
| Caspase-4 |
| Caspase-5 |
| Caspase-6 |
| Caspase-7 |
| Caspase-8 |
| Caspase-9 |
| Caspase-10 |
| Caspase-14 |
| Cathepsins |
Cathepsin B |
| Cathepsin G |
| Cathepsin H |
| Cathepsin K |
| Cathepsin L |
| Cathepsin S |
| Calpains |
Calpains |
Aspartate Proteases
Complex Proteases
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| Cat. No. |
Service |
Price (USD) |
SC1396 |
Custom Protease Assay Services |
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Quotations and Ordering:
 For quotations, you may contact us by email (bioassay@genscript.com), phone (1-732-885-9188 or Toll-Free: 1-877-436-7274), fax (1-732-210-0262), or via our secure online messaging system.
Orders can be placed by email, phone or fax either a PO (Purchase Order) or credit card.
Our customer service representatives are Available 24 hours a day, Monday through Friday to assist you.
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Email: bioassay@genscript.com |
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Phone: 1-877-436-7274 (Toll-Free), 1-732-885-9188 |
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Fax: 1-732-210-0262, 1-732-885-5878 |
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