|Protein || HSV-1 gG, Herpes Simplex Virus Antigen, Recombinant |
|Herpes Simplex Virus-1 gG; || |
|The protein is over 95% pure as determined by 10% PAGE (Coomassie staining). |
|This protein is immunoreactive with the sera of HSV-infected individuals. |
|E. coli |
|Herpes Simplex Virus (HSV)-1 gG is an E. coli-derived recombinant. GenScript Herpes Simplex Virus (HSV)-1 gG contains the HSV-1 gG immunodominant regions. |
|Store the protein at -20°C. Keep container tightly closed. |
|1 mg/ml in 25 mM Tris-HCl, 1 mM EDTA, 50% glycerol |
|The protein will remain stable for one year if stored frozen and for one month if stored in solution at room temperature. |
|The protein makes a good antigen in ELISA and Western Blots, and an excellent antigen for the detection of HSV with minimal specificity problems. |
| Tran LC, Kissner JM et al. A herpes simplex virus 1 recombinant lacking the glycoprotein G coding sequences is defective in entry through apical surfaces of polarized epithelial cells in culture and in vivo. Proc Natl Acad Sci U S A. Feb 2000;97(4):1818-22.|
Sullivan V, Smith GL. Expression and characterization of herpes simplex virus type 1 (HSV-1) glycoprotein G (gG) by recombinant vaccinia virus: neutralization of HSV-1 infectivity with anti-gG antibody. J Gen Virol. Oct 1987;68:2587-98.
Rekabdar E, Tunback P et al. Dichotomy of glycoprotein g gene in herpes simplex virus type 1 isolates. J Clin Microbiol. Sep 2002;40(9):3245-51.