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HSV-1 gG, Herpes Simplex Virus Antigen, Recombinant



*This product has been discontinued! *

Full Name HSV-1 gG, Herpes Simplex Virus Antigen, Recombinant
Abbreviated Name-1
Herpes Simplex Virus-1 gG;
Documents
Description
Herpes Simplex Virus (HSV)-1 gG is an E. coli-derived recombinant. GenScript Herpes Simplex Virus (HSV)-1 gG contains the HSV-1 gG immunodominant regions.
Source
E. coli
Purity
The protein is over 95% pure as determined by 10% PAGE (Coomassie staining).
Storage
Store the protein at -20°C. Keep container tightly closed.
Concentration
1 mg/ml in 25 mM Tris-HCl, 1 mM EDTA, 50% glycerol
Stability
The protein will remain stable for one year if stored frozen and for one month if stored in solution at room temperature.
Specificity
This protein is immunoreactive with the sera of HSV-infected individuals.
Applications
The protein makes a good antigen in ELISA and Western Blots, and an excellent antigen for the detection of HSV with minimal specificity problems.
Sequence
Citation
Tran LC, Kissner JM et al. A herpes simplex virus 1 recombinant lacking the glycoprotein G coding sequences is defective in entry through apical surfaces of polarized epithelial cells in culture and in vivo. Proc Natl Acad Sci U S A. Feb 2000;97(4):1818-22.

Sullivan V, Smith GL. Expression and characterization of herpes simplex virus type 1 (HSV-1) glycoprotein G (gG) by recombinant vaccinia virus: neutralization of HSV-1 infectivity with anti-gG antibody. J Gen Virol. Oct 1987;68:2587-98.

Rekabdar E, Tunback P et al. Dichotomy of glycoprotein g gene in herpes simplex virus type 1 isolates. J Clin Microbiol. Sep 2002;40(9):3245-51.

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