Catalog Products » Recombinant Proteins » Interleukin 13 (IL-13), Human
GenScript Share
 
Search by Catalog Number :
Search by Name :
Search by Sequence : (One letter code)
Search by Category :



Interleukin 13 (IL-13), Human



Cat. No.
Name
Size   
Price
Selected
Z03020-1
1 mg
$4,160

Full Name Interleukin 13 (IL-13), Human
Abbreviated Name-1
NC30 (Human), P600 (Murine);IL-13 (human)
Documents
Interleukin 13 (IL-13), HumanDocument-COA: B60111304_Z03020_COA.pdf (pdf)
Interleukin 13 (IL-13), HumanDocument-MSDS: Z03020_MSDS.pdf (pdf)
Figures
Reference
Description
Interleukin 13 (IL-13) is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and mouse IL-13 is cross-species reactive.
Recombinant human interleukin 13 expressed in CHO cells is glycosylated protein with molecular weight range from 25 to 45 kDa shown in non-reducing SDS-PAGE.
Source
CHO
M.W.
25-45 kDa, observed by non-reducing SDS-PAGE.
Purity
> 95% as analyzed by SDS-PAGE.
Endotoxin Level
< 0.2 EU/μg, determined by LAL method.
Specific Activity
ED50 < 15 ng/ml, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 6.7×105 units/mg.
Storage
Lyophilized recombinant human Interleukin 13 (IL-13) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIL-13 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Formulation
Lyophilized after extensive dialysis against PBS.
Reconstitution
Reconstituted in ddH2O or PBS at 100 μg/ml.
Sequence

S19-N132 (Accession # P35225).

Note
For research use only
1
Custom Recombinant Protein Services: Guaranteed E. coli Expression Package-3 mg purified soluble protein from $2,200 .
2
Bacterial Expression System: GenScript has developed BacPowerTM technologies to tackle hard-to-express and hard-to-dissolve proteins.
3
Yeast Expression System: GenScript's proprietary YeastHIGHTM technology combines the advantages of the bacterial and eukaryotic expression systems.
4
Baculovirus/Insect Cell Expression System: GenScript developed BacuVanceTM platform for the secretion of recombinant proteins from baculovirus-infected insect cells.
5
Mammalian Cell Expression System: The proprietary 293 and CHO suspension system platform promotes fast production and delivery of recombinant proteins and monoclonal antibodies up to grams level.