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Interleukin-6 (IL-6), Rat



Cat. No.
Name
Size   
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Z03041-1
1 mg
$2,100

Full Name Interleukin-6 (IL-6), Rat
Abbreviated Name-1
26 kDa protein, IFN-beta2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
Documents
Interleukin-6 (IL-6), RatDocument-MSDS: Z03041_MSDS.pdf (pdf)
Description
Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, Interleukin-6 (IL-6) has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Interleukin-6 (IL-6) signals through the IL-6 receptor system that consists of two chains, IL-6R alpha and gp130.
Source
293
M.W.
21~26 kDa , observed by reducing SDS-PAGE.
Purity
> 95% as analyzed by SDS-PAGE.
Endotoxin Level
< 0.2 EU/μg, determined by LAL method.
Specific Activity
ED50 < 3 pg/ml, measured by a cell proliferation assay using 7TD1 Cells.
Storage
Lyophilized recombinant Rat Interleukin-6(IL-6) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, it should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Formulation
Lyophilized after extensive dialysis against PBS.
Reconstitution
Reconstituted in ddH2O or PBS at 100 μg/ml.
Sequence
Phe25-Thr211 (Accession # P20607.1)
Note
For research use only
Document-COA
  • B60021305_Z03041_COA.pdf
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