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Interleukin-6 (IL-6), Rat (HEK 293-expressed)



Cat. No.
Name
Size   
Price
Selected
Z03041-1
1 mg
$2,100

Protein Interleukin-6 (IL-6), Rat (HEK 293-expressed)
Synonyms
26 kDa protein, IFN-beta2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
Documents
IL-6, Rat (HEK 293-expressed)Document-MSDS: Z03041_MSDS.pdf (pdf)
Species
Rat
Purity
> 95% as analyzed by SDS-PAGE.
Endotoxin Level
< 0.2 EU/μg, determined by LAL method.
Biological Activity
ED50 < 3 pg/ml, measured by a cell proliferation assay using 7TD1 Cells.
Source
HEK 293
Amino Acid Sequence
FPTSQVRRGD FTEDTTHNRP VYTTSQVGGL ITYVLREILE
MRKELCNGNS DCMNSDDALS ENNLKLPEIQ RNDGCFQTGY
NQEICLLKIC SGLLEFRFYL EFVKNNLQDN KKDKARVIQS
NTETLVHIFK QEIKDSYKIV LPTPTSNALL MEKLESQKEW
LRTKTIQLIL KALEEFLKVT MRSTRQT
Molecular Weight
21~26 kDa , observed by reducing SDS-PAGE.
Description
Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, Interleukin-6 (IL-6) has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Interleukin-6 (IL-6) signals through the IL-6 receptor system that consists of two chains, IL-6R alpha and gp130.
Formulation
Lyophilized after extensive dialysis against PBS.
Reconstitution
Reconstituted in ddH2O or PBS at 100 μg/ml.
Storage
Lyophilized recombinant Rat Interleukin-6(IL-6) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, it should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Note
For research use only
Document-COA
  • B60021305_Z03041_COA.pdf
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