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IL-2 R alpha/CD25, His, Mouse

Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
$370.00
Z04342-100

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Product Introduction
Species Mouse
Protein Construction
IL-2 R alpha/CD25 (Glu22-Lys236)
Accession # P01590		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 25.76 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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IL-2 R Alpha/CD25, His, Mouse

Immobilized IL-2 R alpha/CD25, His, Mouse, His Tag at 5 μg/ml (100 μL/well) on the plate. Dose response curve for Biotinylated Mouse IL-2, His Tag with the EC50 of 0.17 μg/ml determined by ELISA. »

IL-2 R Alpha/CD25, His, Mouse

The purity of IL-2 R alpha/CD25, His, Mouse is greater than 95% as determined by SEC-HPLC. »

IL-2 R Alpha/CD25, His, Mouse

IL-2 R alpha/CD25, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

IL-2 R Alpha/CD25, His, Mouse

IL-2 R alpha/CD25, His, Mouse, His Tag immobilized on CM5 Chip can bind Mouse IL-2, His Tag with an affinity constant of 30.49 nM as determined in SPR assay (Biacore T200). »

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Background
Target Background Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
Synonyms CD25; IDDM10; IL-2 R alpha; IL2R; IL2RA; p55; TCGFR
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.