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NKG2D/CD314, His, Mouse

NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells.
$300.00
Z04344-100

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Product Introduction
Species Mouse
Protein Construction
His NKG2D/CD314 (Phe90-Val232)
Accession # O54709-1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 17.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 24-35kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 20mM Tris, 250mM NaCl (pH 8.0).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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NKG2D/CD314, His, Mouse

Immobilized NKG2D/CD314, His, Mouse, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human MICA, hFc Tag with the EC50 of 70.5 ng/ml determined by ELISA. »

NKG2D/CD314, His, Mouse

The purity of NKG2D/CD314, His, Mouse is greater than 95% as determined by SEC-HPLC. »

NKG2D/CD314, His, Mouse

NKG2D/CD314, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells.
Synonyms CD314; D12S2489E; KLR; NKG2-D; NKG2D
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.