Catalog Products » IL-2 R beta/CD122[Biotin], His, Cynomolgus
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IL-2 R beta/CD122[Biotin], His, Cynomolgus

IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains, and the intermediate affinity complex comprising heterodimers of the beta and gamma chains.
$660.00
Z04372-100

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Product Introduction
Species Cynomolgus
Protein Construction
IL-2 R beta/CD122 (Ala27-Asp239)
Accession # Q38J85		 His
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity IL-2 R beta/CD122[Biotin], His, Cynomolgus captured on CM5 Chip via Anti­His Antibody can bind Human IL­2, No Tag in SPR assay (Biacore T200). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 25.6 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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IL-2 R Beta/CD122[Biotin], His, Cynomolgus

The purity of IL-2 R beta/CD122[Biotin], His, Cynomolgus is greater than 90% as determined by SEC-HPLC. »

IL-2 R Beta/CD122[Biotin], His, Cynomolgus

IL-2 R beta/CD122[Biotin], His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

IL-2 R Beta/CD122[Biotin], His, Cynomolgus

IL-2 R beta/CD122[Biotin], His, Cynomolgus, His Tag captured on CM5 Chip via Anti-His Antibody can bind Human IL-2, No Tag with an affinity constant of 0.148 μM as determined in SPR assay (Biacore T200). »

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Background
Target Background IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains, and the intermediate affinity complex comprising heterodimers of the beta and gamma chains.
Synonyms CD122; IL-15 R beta; IL-2 R beta; IL-2R subunit beta; IL2RB; P70-75; p75; RP5-1170K4.6; IL-15 R β; IL-2 R β; IL-2R subunit β
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.