Catalog Products » IL-1 Rrp2/IL-1 R6[Biotin], His & Avi, Human
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Manual
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IL-1 Rrp2/IL-1 R6[Biotin], His & Avi, Human

The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.
$660.00
Z04488-100

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Product Introduction
Species Human
Protein Construction
IL-1 Rrp2/IL-1 R6 (Asp20-Arg335)
Accession # Q9HB29-1		 His Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 39.1 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-75 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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IL-1 Rrp2/IL-1 R6[Biotin], His & Avi, Human

Immobilized IL-1 Rrp2/IL-1 R6[Biotin], His & Avi, Human, His Tag at 0.5 μg/ml(100 μl/well) on the streptavidin precoated plate(5 μg/ml). Dose response curve for Anti-IL-1 Rrp2 Antibody, hFc Tag with the EC50 of 6.1 ng/ml determined by ELISA. »

IL-1 Rrp2/IL-1 R6[Biotin], His & Avi, Human

The purity of IL-1 Rrp2/IL-1 R6[Biotin], His & Avi, Human is greater than 90% as determined by SEC-HPLC. »

IL-1 Rrp2/IL-1 R6[Biotin], His & Avi, Human

IL-1 Rrp2/IL-1 R6[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.
Synonyms IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.