Catalog Products » IL-17R alpha/CD217 hFc Chimera[Biotin], Avi, Human
Manual
Manual
COAs

IL-17R alpha/CD217 hFc Chimera[Biotin], Avi, Human

Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.
$660.00
Z04500-100

Ask us a question
Product Introduction
Species Human
Protein Construction
IL-17R alpha/CD217 (Leu33-Trp320)
Accession # Q96F46-1		 hFc Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 61.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 78-100 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
Back

IL-17R Alpha/CD217 HFc Chimera[Biotin], Avi, Human

Immobilized Human IL-17A, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for IL-17R alpha/CD217 hFc Chimera[Biotin], Avi, Human, hFc Avi Tag with the EC50 of 0.17 μg/ml determined by ELISA. »

IL-17R Alpha/CD217 HFc Chimera[Biotin], Avi, Human

The purity of IL-17R alpha/CD217 hFc Chimera[Biotin], Avi, Human is greater than 90% as determined by SEC-HPLC. »

IL-17R Alpha/CD217 HFc Chimera[Biotin], Avi, Human

IL-17R alpha/CD217 hFc Chimera[Biotin], Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

<
>

Background
Target Background Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.
Synonyms CD217; CDw217; IL-17RA; IL17R; CANDF5; IL-7R; IL-7R-alpha; ILRA
Back

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.