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SKP1[Biotin], His & Avi, Human

The S-phase Kinase-Associated Protein 1 (SKP1) is a core component of the SKP1, Cullin 1, F-box protein (SCF) complex, an E3 ubiquitin ligase that serves to poly-ubiquitinate a vast array of protein targets as a signal for their proteasomal degradation, thereby playing a critical role in the regulation of downstream biological processes.
$660.00
Z04613-100

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Product Introduction
Species Human
Protein Construction
His SKP1 (Pro2-Lys163)
Accession # P63208-1		 Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 21.43 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 23-28 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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SKP1[Biotin], His & Avi, Human

The purity of SKP1[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC. »

SKP1[Biotin], His & Avi, Human

SKP1[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background The S-phase Kinase-Associated Protein 1 (SKP1) is a core component of the SKP1, Cullin 1, F-box protein (SCF) complex, an E3 ubiquitin ligase that serves to poly-ubiquitinate a vast array of protein targets as a signal for their proteasomal degradation, thereby playing a critical role in the regulation of downstream biological processes.
Synonyms p19A; OCP-2; OCP-II; SIII; EMC19; OCP2; SKP1A; TCEB1L
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.