uPAR/PLAUR[Biotin], His & Avi, Human

The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.

Price	$660.00
Cat. No.	Z04641-100
Size	100 μg 500 μg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Human

Protein Construction

uPAR/PLAUR (Leu23-Gly305) Accession # Q03405-1	His	Avi
N-term		C-term

Conjugate

Biotin

Purity

> 95% as determined by BisTris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.

Expression System

HEK293

Theoretical Molecular Weight

34.36 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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Immobilized Human PLAU (active form), His Tag at 2 μg /ml (100 μl /well) on the plate. Dose response curve for uPAR/PLAUR[Biotin], His & Avi, Human, His Avi Tag with the EC50 of 16.0ng/ml determined by ELISA. »

The purity of uPAR/PLAUR[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC. »

uPAR/PLAUR[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Background

Target Background	The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
Synonyms	U-PAR; uPAR; CD87; PLAUR; MO3; UPAR

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.