TK1, His, Canine

Thymidine kinase 1 (TK1) catalyzes the initial phosphorylation of thymidine in the salvage pathway synthesis of dTTP, an essential building block of DNA. TK1 is a cytosolic enzyme with its highest level during the S-phase of the cell cycle.

Price	$390.00
Cat. No.	Z04720-100
Size	100 μg 500 μg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Canine

Protein Construction

TK1 (Ser2-Asn242) Accession # E2QXP4	His
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Expression System

E.coli

Theoretical Molecular Weight

27.41 kDa

Apparent Molecular Weight

The protein migrates to 25-28 kDa based on Bis-Tris PAGE result.

Formulation

Supplied as 0.22μm filtered solution in 20mM PB, 500mM NaCl, 200mM L-arginine (pH 7.4).

Concentration

Verified by one or more methods from A280/Bioactivity/BCA/Bradford.

Storage & Stability

This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.

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Background

Target Background	Thymidine kinase 1 (TK1) catalyzes the initial phosphorylation of thymidine in the salvage pathway synthesis of dTTP, an essential building block of DNA. TK1 is a cytosolic enzyme with its highest level during the S-phase of the cell cycle.
Synonyms	Thymidine kinase; EC 2.7.1.21; thymidine kinase-1

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.