SERPINF2/A2AP, His, Cynomolgus

Large-pool solvent/detergent (SD) plasma for transfusion exhibits reduced alpha 2-antiplasmin (alpha2-AP; SERPINF2) functional activity. The reason for the loss of alpha2-AP has not been described and could be due to the SD incubation itself and/or to the processing steps implemented to remove the solvent and the detergent.

Price	$390.00
Cat. No.	Z04910-100
Size	100 μg 500 μg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Cynomolgus

Protein Construction

SERPINF2/A2AP (Met27-Lys490) Accession # A0A2K5WNU6	His
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin Level

Less than 0.1 EU per μg by the LAL method.

Biological Activity

Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.

Expression System

HEK293

Theoretical Molecular Weight

52.83 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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Immobilized SERPINF2/A2AP, His, Cynomolgus, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-SERPINF2 Antibody, hFc Tag with the EC50 of 53.5ng/ml determined by ELISA. »

The purity of SERPINF2/A2AP, His, Cynomolgus is greater than 95% as determined by SEC-HPLC. »

SERPINF2/A2AP, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Background

Target Background	Large-pool solvent/detergent (SD) plasma for transfusion exhibits reduced alpha 2-antiplasmin (alpha2-AP; SERPINF2) functional activity. The reason for the loss of alpha2-AP has not been described and could be due to the SD incubation itself and/or to the processing steps implemented to remove the solvent and the detergent.
Synonyms	Alpha-2-AP; AAP; PLI; SERPINF2; A2AP; ALPHA-2-PI; API; Serpin F2

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.