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Serum Albumin, His, Cynomolgus

Albumins are multifunctional proteins present in the blood serum of animals. They can bind and transport a wide variety of ligands which they accommodate due to their conformational flexibility. Serum albumins are highly conserved both in amino acid sequence and three-dimensional structure. Several mammalian and avian serum albumins (SAs) are also allergens. Sensitization to one of the SAs coupled with the high degree of conservation between SAs may result in cross-reactive antibodies in allergic individuals.
$220.00
Z04911-100

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Product Introduction
Species Cynomolgus
Protein Construction
Serum Albumin (Asp25-Ala608)
Accession # A2V9Z4-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1 EU per μg by the LAL method.
Biological Activity Serum Albumin, His, Cynomolgus immobilized on CM5 Chip can bind Biotinylated Cynomolgus FcRn, His-Avi Tag in SPR assay (Biacore S200). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 67.1 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 68-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/ml for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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Serum Albumin, His, Cynomolgus

The purity of Serum Albumin, His, Cynomolgus is greater than 95% as determined by SEC-HPLC. »

Serum Albumin, His, Cynomolgus

Serum Albumin, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Serum Albumin, His, Cynomolgus

Serum Albumin, His, Cynomolgus, His Tag immobilized on CM5 Chip can bind Cynomolgus/Rhesus macaque FcRn, His Tag with an affinity constant of 0.13 μM as determined in SPR assay (Biacore T200). »

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Background
Target Background Albumins are multifunctional proteins present in the blood serum of animals. They can bind and transport a wide variety of ligands which they accommodate due to their conformational flexibility. Serum albumins are highly conserved both in amino acid sequence and three-dimensional structure. Several mammalian and avian serum albumins (SAs) are also allergens. Sensitization to one of the SAs coupled with the high degree of conservation between SAs may result in cross-reactive antibodies in allergic individuals.
Synonyms Albumin; ALB; Serum albumin; ANALBA; FDAH; PRO0883; PRO0903; PRO1341
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.