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TSLPR, His, Cynomolgus

Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
$390.00
Z04938-100

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Product Introduction
Species Cynomolgus
Protein Construction
TSLPR (Gln23-Lys231)
Accession # XP_045239630.1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 25.42 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 42-52 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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TSLPR, His, Cynomolgus

Immobilized TSLPR, His, Cynomolgus, His Tag at 2 μg /ml (100 μl/well) on the plate. Dose response curve for Biotinylated Cynomolgus TSLP, His Tag with the EC50 of 0.15 μg /ml determined by ELISA. »

TSLPR, His, Cynomolgus

Immobilized TSLPR, His, Cynomolgus, His Tag at 0.5 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-TSLPR Antibody, hFc Tag with the EC50 of 13.5ng/ml determined by ELISA. »

TSLPR, His, Cynomolgus

The purity of TSLPR, His, Cynomolgus is greater than 95% as determined by SEC-HPLC. »

TSLPR, His, Cynomolgus

TSLPR, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
Synonyms TSLP receptor; TSLPR; CRL2; CRLF2Y; CRLF2; IL-XR; p2RY8/CRLF2 fusion; CRLF2
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.