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uPAR/PLAUR, His, Cynomolgus

The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
$280.00
Z04940-100

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Product Introduction
Species Cynomolgus
Protein Construction
uPAR/PLAUR (Leu23-Gly305)
Accession # Q9GK78		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 32.69 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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UPAR/PLAUR, His, Cynomolgus

Immobilized uPAR/PLAUR, His, Cynomolgus, His Tag at 2 μg /ml (100 μl /well) on the plate. Dose response curve for Biotinylated Human PLAU, His Avi Tag with the EC50 of 21.0ng/ml determined by ELISA. »

UPAR/PLAUR, His, Cynomolgus

The purity of uPAR/PLAUR, His, Cynomolgus is greater than 95% as determined by SEC-HPLC. »

UPAR/PLAUR, His, Cynomolgus

uPAR/PLAUR, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

UPAR/PLAUR, His, Cynomolgus

uPAR/PLAUR, His, Cynomolgus, His Tag immobilized on CM5 Chip can bind Cynomolgus PLAU, His Tag with an affinity constant of 0.033 nM as determined in SPR assay (Biacore T200). »

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Background
Target Background The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
Synonyms U-PAR; uPAR; CD87; PLAUR; MO3; UPAR
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.