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CEACAM-3/CD66d, His, Human

The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM)3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3 and is characterized by rapid stimulation of the GTPase Rac.
$340.00
Z05162-100

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Product Introduction
Species Human
Protein Construction
CEACAM-3/CD66d (Lys35-Gly155)
Accession # P40198-1		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 14.19 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 17-27 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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CEACAM-3/CD66d, His, Human

CEACAM-3/CD66d, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

CEACAM-3/CD66d, His, Human

Immobilized CEACAM-3/CD66d, His, Human, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human CEACAM-7, hFc Tag with the EC50 of 26.0ng/ml determined by ELISA. »

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Background
Target Background The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM)3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3 and is characterized by rapid stimulation of the GTPase Rac.
Synonyms CEACAM3; CD66d; CGM1; CEA;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.