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CEACAM-8/CD66b, His, Human

Eosinophils and their products are likely important in the pathophysiology of allergic diseases, such as bronchial asthma, and in host immunity to parasitic organisms. CD66b (CEACAM8, CGM6, NCA-95) is a single chain, GPI-anchored, highly glycosylated protein belonging to the carcinoembryonic Ag supergene family. CD66b is an activation marker for human granulocytes.
$300.00
Z05166-100

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Product Introduction
Species Human
Protein Construction
CEACAM-8/CD66b (Gln35-Ser319)
Accession # NP_001807.2		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 32.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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CEACAM-8/CD66b, His, Human

The purity of CEACAM-8/CD66b, His, Human is greater than 95% as determined by SEC-HPLC. »

CEACAM-8/CD66b, His, Human

CEACAM-8/CD66b, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

CEACAM-8/CD66b, His, Human

CEACAM-8/CD66b, His, Human, His Tag immobilized on CM5 Chip can bind Human CEACAM-6, His Tag with an affinity constant of 4.59 μM as determined in SPR assay (Biacore T200). »

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Background
Target Background Eosinophils and their products are likely important in the pathophysiology of allergic diseases, such as bronchial asthma, and in host immunity to parasitic organisms. CD66b (CEACAM8, CGM6, NCA-95) is a single chain, GPI-anchored, highly glycosylated protein belonging to the carcinoembryonic Ag supergene family. CD66b is an activation marker for human granulocytes.
Synonyms CD66b; CEACAM8; CGM6; CD67; NCA-95
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.