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CTGF/CCN2 hFc Chimera, Human

Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells.
$390.00
Z05199-100

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Product Introduction
Species Human
Protein Construction
hFc CTGF/CCN2 (Gln27-Ala349)
Accession # Q5M8T4
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 61.77 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-55 kDa and 62-72 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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CTGF/CCN2 HFc Chimera, Human

Immobilized CTGF/CCN2 hFc Chimera, Human, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-CTGF Antibody, hFc Tag with the EC50 of 25.8ng/ml determined by ELISA. »

CTGF/CCN2 HFc Chimera, Human

The purity of CTGF/CCN2 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »

CTGF/CCN2 HFc Chimera, Human

CTGF/CCN2 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells.
Synonyms IGFBP8; IBP-8; CCN2; NOV2; HCS24; CTGF; CTGRP; Fisp12; MGC102839
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.