CXCL4 hFc Chimera, Human

Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes.

Price	$370.00
Cat. No.	Z05207-100
Size	100 μg 500 μg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Human

Protein Construction

CXCL4 (Glu32-Ser101) Accession # P02776	hFc
N-term	C-term

Purity

> 95% as determined by BisTris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Expression System

HEK293

Theoretical Molecular Weight

34.5 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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The purity of CXCL4 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC »

CXCL4 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Background

Target Background

Synonyms

PF-4; Oncostatin-A; CXCL4; SCYB4; Iroplact; MGC138298

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.