Catalog Products » DNAM-1/CD226, His & Avi, Human
Manual
Manual
COAs

DNAM-1/CD226, His & Avi, Human

DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
$250.00
Z05225-100

Ask us a question
Product Introduction
Species Human
Protein Construction
DNAM-1/CD226 (Glu19-Asn247)
Accession # Q15762		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 28.9 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 45-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
Back

DNAM-1/CD226, His & Avi, Human

Immobilized DNAM-1/CD226, His & Avi, Human, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human CD155, mFc Tag with the EC50 of 0.16 μg/ml determined by ELISA. »

DNAM-1/CD226, His & Avi, Human

The purity of DNAM-1/CD226, His & Avi, Human is greater than 95% as determined by SEC-HPLC. »

DNAM-1/CD226, His & Avi, Human

DNAM-1/CD226, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

DNAM-1/CD226, His & Avi, Human

Human CD155, hFc Tag captured on Protein A chip, can bind DNAM-1/CD226, His & Avi, Human, His Tag with an affinity constant of 0.22μM as determined in a SPR assay (Biacore T200). »

<
>

Background
Target Background DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
Synonyms CD226 molecule; CD226; DNAM1; PTA1; TLiSA1
Back

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.