Catalog Products » E-Selectin/CD62E hFc Chimera, Human
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E-Selectin/CD62E hFc Chimera, Human

E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.
$220.00
Z05264-100

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Product Introduction
Species Human
Protein Construction
E-Selectin/CD62E (Trp22-Pro556)
Accession # P16581		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 0.1 EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 85.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 110-140kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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E-Selectin/CD62E HFc Chimera, Human

Immobilized E-Selectin/CD62E hFc Chimera, Human, hFc Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-E-Selectin Antibody, hFc Tag with the EC50 of 31.4ng/ml determined by ELISA. »

E-Selectin/CD62E HFc Chimera, Human

The purity of E-Selectin/CD62E hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »

E-Selectin/CD62E HFc Chimera, Human

E-Selectin/CD62E hFc Chimera, Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. »

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Background
Target Background E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.
Synonyms CD62E; ELAM; ELAM1; ESEL; E-Selectin; LECAM2; SELE; selectin E; RP1-117P20.2
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.