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FGF-7/KGF, His, Human

The expression patterns of mRNAs encoding Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling may play a role in regulating ureteric bud growth.t Results of these studies demonstrate that the developing ureteric bud and mature collecting system of FGF-7-null kidneys is markedly smaller than wild type. FGF-7 levels modulate the extent of ureteric bud growth during development and the number of nephrons that eventually form in the kidney.
$370.00
Z05292-100

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Product Introduction
Species Human
Protein Construction
His FGF-7/KGF (Cys32-Thr194)
Accession # P21781-1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 0.1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System E.coli
Theoretical Molecular Weight 20.1 kDa
Apparent Molecular Weight The protein has a predicted MW of 20.1 kDa same as Bis-Tris PAGE result.
Formulation Supplied as 0.22 μm filtered solution in 50 mM Tris, 250 mM NaCl (pH 7.5).
Concentration Verified by one or more methods from A280/Bioactivity/BCA/Bradford.
Storage & Stability Upon receiving, the product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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FGF-7/KGF, His, Human

Immobilized FGF-7/KGF, His, Human, His Tag at 5 μg /ml (100 μl/well) on the plate. Dose response curve for Human FGFR2 beta (IIIb), hFc Tag with the EC50 of 1.22 μg /ml determined by ELISA. »

FGF-7/KGF, His, Human

The purity of FGF-7/KGF, His, Human is greater than 95% as determined by SEC-HPLC. »

FGF-7/KGF, His, Human

FGF-7/KGF, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

FGF-7/KGF, His, Human

FGF-7/KGF, His, Human, His Tag immobilized on CM5 Chip can bind Human FGFR2 beta (IIIb) , His Tag with an affinity constant of 18.91 nM as determined in SPR assay (Biacore T200). »

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Background
Target Background The expression patterns of mRNAs encoding Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling may play a role in regulating ureteric bud growth.t Results of these studies demonstrate that the developing ureteric bud and mature collecting system of FGF-7-null kidneys is markedly smaller than wild type. FGF-7 levels modulate the extent of ureteric bud growth during development and the number of nephrons that eventually form in the kidney.
Synonyms FGF-7; HBGF-7; KGF; FGF7
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.