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FGL1 hFc Chimera, Human

Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3.
$390.00
Z05301-100

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Product Introduction
Species Human
Protein Construction
hFc FGL1 (Asp64-Asn305)
Accession # Q08830
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 54.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-66 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in 20mM PB, 250mM NaCl (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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FGL1 HFc Chimera, Human

Immobilized Human LAG3, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for FGL1 hFc Chimera, Human, hFc Tag with the EC50 of 0.19 μg/ml determined by ELISA. »

FGL1 HFc Chimera, Human

The purity of FGL1 hFc Chimera, Human is greater than 90% as determined by SEC-HPLC. »

FGL1 HFc Chimera, Human

FGL1 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3.
Synonyms FGL1; FGL-1; Hepassocin; HP-041; HFREP-1; LFIRE-1; HFREP1; Lag3 ligand
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.