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IGFI hFc Chimera, Human

The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins.Insulin-like growth factor I (IGF-I) is a polypeptide hormone produced mainly by the liver in response to the endocrine GH stimulus, but it is also secreted by multiple tissues for autocrine/paracrine purposes.
$190.00
Z05413-100

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Product Introduction
Species Human
Protein Construction
hFc IGFI (Gly49-Ala118)
Accession # P05019-1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 33.18 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 38-43 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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IGFI HFc Chimera, Human

Immobilized Human IGF1R, His Tag at 5 μg /ml(100 μl/well) on the plate. Dose response curve for IGFI hFc Chimera, Human, hFc Tag with the EC50 of 0.68 μg /ml determined by ELISA. »

IGFI HFc Chimera, Human

The purity of IGFI hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »

IGFI HFc Chimera, Human

IGFI hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

IGFI HFc Chimera, Human

Human IGFBP-3, His Tag captured on CM5 Chip via anti-his antibody can bind IGFI hFc Chimera, Human, hFc Tag with an affinity constant of 2.32 nM as determined in SPR assay (Biacore T200). »

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Background
Target Background The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins.Insulin-like growth factor I (IGF-I) is a polypeptide hormone produced mainly by the liver in response to the endocrine GH stimulus, but it is also secreted by multiple tissues for autocrine/paracrine purposes.
Synonyms IGF-I; MGF; IBP1; IGF1A;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.