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IL-13Ra1, His, Human

Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.
$340.00
Z05436-100

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Product Introduction
Species Human
Protein Construction
IL-13Ra1 (Gly22-Thr343)
Accession # P78552-1		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Loaded Human IL­13, hFc Tag on ProA­Biosensor can bind Human IL­13Ra1, His Tag in BLI assay (Gator® Prime). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 37.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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IL-13Ra1, His, Human

IL-13Ra1, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

IL-13Ra1, His, Human

Human IL-13, No Tag immobilized on CM5 Chip can bind IL-13Ra1, His, Human, His Tag with an affinity constant of 0.55 μM as determined in SPR assay (Biacore T200). »

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Background
Target Background Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.
Synonyms IL-13 R alpha 1; IL13R; IL13RA; CT19; IL13RA1; NR4; CD213A1; AI882074
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.