Catalog Products » IL-4 R alpha/CD124 hFc Chimera, Human
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IL-4 R alpha/CD124 hFc Chimera, Human

Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family. The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.
$300.00
Z05504-100

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Product Introduction
Species Human
Protein Construction
IL-4 R alpha/CD124 (Met26-His232)
Accession # P24394-1		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 50.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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IL-4 R Alpha/CD124 HFc Chimera, Human

Immobilized Human IL-4, No Tag at 1 μg/ml(100 μl/well) on the plate. Dose response curve for IL-4 R alpha/CD124 hFc Chimera, Human, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA. »

IL-4 R Alpha/CD124 HFc Chimera, Human

The purity of IL-4 R alpha/CD124 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »

IL-4 R Alpha/CD124 HFc Chimera, Human

IL-4 R alpha/CD124 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family. The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.
Synonyms CD124; IL-4 R alpha; IL-4R subunit alpha; IL4R; IL-4Ra; IL4RACD124
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.