Catalog Products » LIV-1/SLC39A6 hFc Chimera, Human
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LIV-1/SLC39A6 hFc Chimera, Human

Zinc transporter ZIP6 (SLC39A6) or LIV-1 is a protein that belongs to a subfamily of proteins group that displays structural specifications of zinc transporters in the cell membrane. Overexpression of this protein is observed in breast, prostate, and kidney tumor cells. Lately, LIV-1 is a dependable marker for detection of estrogen receptor positive breast cancer, which can be used to detect luminal breast cancer type A.
$470.00
Z05605-100

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Product Introduction
Species Human
Protein Construction
LIV-1/SLC39A6 (Phe29-Trp325)_x000D_
Accession # Q13433-1		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 60.39 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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LIV-1/SLC39A6 HFc Chimera, Human

Immobilized LIV-1/SLC39A6 hFc Chimera, Human, hFc Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-LIV-1 Antibody, hFc Tag with the EC50 of 69.5ng/ml determined by ELISA. »

LIV-1/SLC39A6 HFc Chimera, Human

The purity of LIV-1/SLC39A6 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »

LIV-1/SLC39A6 HFc Chimera, Human

LIV-1/SLC39A6 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background Zinc transporter ZIP6 (SLC39A6) or LIV-1 is a protein that belongs to a subfamily of proteins group that displays structural specifications of zinc transporters in the cell membrane. Overexpression of this protein is observed in breast, prostate, and kidney tumor cells. Lately, LIV-1 is a dependable marker for detection of estrogen receptor positive breast cancer, which can be used to detect luminal breast cancer type A.
Synonyms ZIP-6; LIV-1; SLC39A6; LIV1; ZIP6
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.