NKG2C&CD94, His & Avi, Flag Human

NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the NK-cell expansion.

Price	$390.00
Cat. No.	Z05688-100
Size	100 μg 500 μg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Human

Protein Construction

Avi	His	NKG2C&CD94 (Glu98-Leu231(NKG2C)&Ser34-Ile179(CD94))_x000D_ Accession # P26717(NKG2C)&Q13241-1(CD94)
N-term		C-term

Purity

> 95% as determined by BisTris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Expression System

HEK293

Theoretical Molecular Weight

15.3kDa (NKG2C)&17.9kDa (CD94)

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 30-50 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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The purity of NKG2C&CD94, His & Avi, Flag Human is greater than 95% as determined by SEC-HPLC. »

NKG2C&CD94, His & Avi, Flag Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%. »

NKG2C&CD94, His & Avi, Flag Human, His Tag immobilized on CM5 Chip can bind Human HLA-E*01:03 Complex Tetramer, His Tag with an affinity constant of 1.65 μM as determined in SPR assay (Biacore T200). »

Background

Target Background	NKG2C&CD94 is a C-type lectin heterodimer on NK cells and CD8+ cytotoxic T-cells, it can recognize peptides derived from the intracellular proteins in the context of HLA-E. NKG2C&CD94 itself has no signal transduction function but is an activating receptor on the surface of NK cells that involved in driving the NK-cell expansion.
Synonyms	NKG2C&CD94; NKG2C; CD94

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.