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TEM1/cd248, His, Human

Colorectal cancer (CRC) is one of the most common cancers worldwide usually diagnosed in the advanced stage. The serum concentration of tumor endothelial marker 1 (TEM1) was measured and correlated with clinicopathological features to evaluate whether TEM1 might serve as a biomarker for early CRC diagnosis, progression, and prognosis. TEM1 can act as a potential diagnostic, progression, and prognostic serum biomarker for patients with CRC; TEM1 might be a good supplement for commonly used markers CEA and Ca 19-9.
$390.00
Z05864-100

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Product Introduction
Species Human
Protein Construction
TEM1/cd248 (Gln18-Leu687)_x000D_
Accession # Q9HCU0-1		 His
N-term C-term
Purity > 90% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 72.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 125-155 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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TEM1/cd248, His, Human

Immobilized TEM1/cd248, His, Human, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-TEM1 Antibody, hFc Tag with the EC50 of 1.4ng/ml determined by ELISA. »

TEM1/cd248, His, Human

The purity of TEM1/cd248, His, Human is greater than 90% as determined by SEC-HPLC. »

TEM1/cd248, His, Human

TEM1/cd248, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background Colorectal cancer (CRC) is one of the most common cancers worldwide usually diagnosed in the advanced stage. The serum concentration of tumor endothelial marker 1 (TEM1) was measured and correlated with clinicopathological features to evaluate whether TEM1 might serve as a biomarker for early CRC diagnosis, progression, and prognosis. TEM1 can act as a potential diagnostic, progression, and prognostic serum biomarker for patients with CRC; TEM1 might be a good supplement for commonly used markers CEA and Ca 19-9.
Synonyms Endosialin; CD248; CD164L1; TEM1; CD164 sialomucin-like 1; CD164L1; CD248 molecule; MGC119479
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.