TIM-4, His, Human

Tim4 is a transmembrane protein as the phosphatidylserine (PS) receptor, known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed highly in macrophages, and macrophage Tim-4 inhibits inflammation under various conditions of immune activation.

Price	$340.00
Cat. No.	Z05885-100
Size	100 μg 500 μg Buy in bulk
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Product Introduction Background Bottom Notes

Product Introduction

Species

Human

Protein Construction

TIM-4 (Glu25-Gln314)_x000D_ Accession # Q96H15-1	His
N-term	C-term

Purity

> 95% as determined by BisTris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Expression System

HEK293

Theoretical Molecular Weight

32.43 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 78-98 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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The purity of TIM-4, His, Human is greater than 95% as determined by SEC-HPLC. »

TIM-4, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

Background

Target Background	Tim4 is a transmembrane protein as the phosphatidylserine (PS) receptor, known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed highly in macrophages, and macrophage Tim-4 inhibits inflammation under various conditions of immune activation.
Synonyms	TIMD-4; TIMD4; TIM-4;TIM4

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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.