Catalog Products » Transferrin R/CD71 hFc Chimera, Human
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Transferrin R/CD71 hFc Chimera, Human

The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
$280.00
Z05918-100

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Product Introduction
Species Human
Protein Construction
Transferrin R/CD71 (Cys89-Phe760)_x000D_
Accession # P02786-1		 hFc
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 101.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 105-115 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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Transferrin R/CD71 HFc Chimera, Human

Immobilized Transferrin R/CD71 hFc Chimera, Human, hFc Tag at 2 μg/ml(100 μl/well) on the plate. Dose response curve for Biotinylated Anti-Transferrin R Antibody, hFc Avi Tag with the EC50 of 25.8ng/ml determined by ELISA. »

Transferrin R/CD71 HFc Chimera, Human

Transferrin R/CD71 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
Synonyms TR; TfR1; CD71; sTfR; T9; p90; TFRC; TFR
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.