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UBASH3B/STS1, His, Human

UBASH3/STS/TULA is a novel two-member family, which exerts several key regulatory effects in multiple cell types. UBASH3B/STS-1/TULA-2 is a highly active protein tyrosine phosphatase; its major target appears to be a specific regulatory site of protein tyrosine kinases of the Syk family, dephosphorylation of which inhibits Syk and Zap-70 kinases and suppresses receptor signaling mediated by these kinases.
$370.00
Z05937-100

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Product Introduction
Species Human
Protein Construction
His UBASH3B/STS1 (Gly380-Glu649)_x000D_
Accession # Q8TF42
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System E.coli
Theoretical Molecular Weight 31.88 kDa
Apparent Molecular Weight The protein has a predicted MW of 31.88 kDa same as Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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UBASH3B/STS1, His, Human

The purity of UBASH3B/STS1, His, Human is greater than 95% as determined by SEC-HPLC. »

UBASH3B/STS1, His, Human

UBASH3B/STS1, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background UBASH3/STS/TULA is a novel two-member family, which exerts several key regulatory effects in multiple cell types. UBASH3B/STS-1/TULA-2 is a highly active protein tyrosine phosphatase; its major target appears to be a specific regulatory site of protein tyrosine kinases of the Syk family, dephosphorylation of which inhibits Syk and Zap-70 kinases and suppresses receptor signaling mediated by these kinases.
Synonyms STS-1; UBASH3B; TULA-2; TULA 2; TULA2; KIAA1959; p70;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.