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ULBP-1, His & Avi, Human

ULBP-1, or UL16-binding protein 1, is a protein that plays a significant role in the immune system, particularly in the recognition and elimination of abnormal cells, such as those found in cancer. It is a ligand for the NKG2D receptor, which is expressed on the surface of natural killer (NK) cells and certain T cells. The interaction between ULBP-1 and NKG2D can activate these immune cells, leading to the destruction of target cells.
$390.00
Z05938-100

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Product Introduction
Species Human
Protein Construction
ULBP-1 (Gly26-Pro215)_x000D_
Accession # Q9BZM6		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1 EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 25.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 28-35 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in 20 mM PB, 0.5 M NaCl, 0.1 M L-arginine (pH 8.0).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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ULBP-1, His & Avi, Human

Immobilized ULBP-1, His & Avi, Human, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.22μg/ml determined by ELISA. »

ULBP-1, His & Avi, Human

The purity of ULBP-1, His & Avi, Human is greater than 95% as determined by SEC-HPLC. »

ULBP-1, His & Avi, Human

ULBP-1, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background ULBP-1, or UL16-binding protein 1, is a protein that plays a significant role in the immune system, particularly in the recognition and elimination of abnormal cells, such as those found in cancer. It is a ligand for the NKG2D receptor, which is expressed on the surface of natural killer (NK) cells and certain T cells. The interaction between ULBP-1 and NKG2D can activate these immune cells, leading to the destruction of target cells.
Synonyms ALCAN-beta; NKG2D ligand 1; N2DL-1; NKG2DL1; MULT-1; NKG2DL; AET1I; ULBP1; ULBP-1;ALCAN-β
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.