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BDNF, Human/Mouse/Rat

The brain-derived neurotrophic factor (BDNF) is a secretory growth factor that promotes neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the central nervous system. Brain-derived neurotrophic factor biosynthesis and secretion are chrono-topically regulated processes at the cellular level, accounting for specific localizations and functions.
$370.00
Z05971-100

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Product Introduction
Species Human/Mouse/Rat
Protein Construction
BDNF (His129-Arg247(Human) / His131-Arg249(Mouse/Rat))_x000D_
Accession # P23560-1(Human) / P21237-1(Mouse) / P23363(Rat)
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 0.05 EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System E.coli
Theoretical Molecular Weight 13.51 kDa
Apparent Molecular Weight The protein migrates to 15-19 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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BDNF, Human/Mouse/Rat

Immobilized BDNF, Human/Mouse/Rat No Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human TrkB, His Tag with the EC50 of 0.39 μg/ml determined by ELISA. »

BDNF, Human/Mouse/Rat

BDNF, Human/Mouse/Rat on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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Background
Target Background The brain-derived neurotrophic factor (BDNF) is a secretory growth factor that promotes neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the central nervous system. Brain-derived neurotrophic factor biosynthesis and secretion are chrono-topically regulated processes at the cellular level, accounting for specific localizations and functions.
Synonyms Abrineurin; BDNF; ANON2; BULN2
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.